Piper hispidum
Amides:
- N-[7-(30,40-methylenedioxyphenyl)-2(Z),4(Z) heptadienoyl] pyrrolidine (1)
- (3Z,5Z)-N-isobutyl- 8-(30,40-methylenedioxyphenyl)- heptadienamide (1)
Both of these compounds were isolated from P. hispidum leaves. These amides have been shown to have antifungal properties (Alecio et al., 1998).
- 3Z,5Z)-N-isobutyl-8-(30,40-methylenedioxy-phenyl)-heptadienamide (2)
- N-[3-(60-methoxy-30,40-methy-lenedioxyphenyl)-2(Z)-propenoyl]pyrrolidine (2)
- piper-amine (2)
These amides were isolated from stems of P. hispidum, and have been shown to possess antifungal properties (Navickiene et al., 2000). For strucutral drawings and further information, see attached pdf.
Butenolides:
- 9,10-methylenedioxy-5,6-Z-fadyenolide (3)
This Butenolide was isolated from the leaves of P. hispidum (Michela et al., 2010).
Terpenes:
- alpha-copaene (4)
- alpha-pinene (4)
- beta-pinene (4)
- (E)-nerolidol (4)
- trans-caryophyllene (4)
- Camphene (9)
- alpha-elemene (9)
These sesquiterpenes were isolated from ripe and unripe fruit of P. hispidum (Simeone et a., 2011).
Propenylphenols:
- Pseudodillapiole (5, 6, 7, 8)
Chalcones and Dihydrochalcones:
- 2’,3’-Dihydroxy-4’,6’-dimethoxychalcone (10)
- 2’,6’-Dihydroxy-4’-methoxydihydrochalcone (5, 7)
- 2’-Hydroxy-3’,4’,6’-trimethoxychalcone (10)
Flavanones:
- 6-Hydroxy-5,7-dimethoxytlavanone (10)
- 8-Hydroxy-5,7-dimethoxytlavanone (10)
- Pinostrobin (5, 7)
- 5,7,8-Trimethoxyflavanone (10)
Works Cited:
1) Alecio, Bolzani A C, Young, M.C.M., “Antifungal amide from leaves of Piper hispidum”, Journal of Natural Products, 1998.61, 637–639.
2) Hosana Maria D. Navickiene, Alberto Camilo Alecio, Massuo Jorge Kato, Vanderlan da S. Bolzani, Maria Claudia M. Young, Alberto Jose Cavalheiro, Maysa Furlan (2000) "Antifungal Amides from Piper hispidum and Piper tuberculatum", Phytochemistry, 55: 621-626.
3) Joanna L. Michela, Yegao Chen, Hongjie Zhang (2010) “Estrogenic and serotonergic butenolides from the leaves of Piper hispidum Swingle (Piperaceae)”, Journal of Ethnopharmacology, 129: 220–226.
4) Maria Lúcia Ferreira Simeone, Sandra Bos Mikich, Lílian Cristina Côcco, Fabrício Augusto Hansel, Gledson Vigiano Bianconi (2011) "Chemical Composition of Essential Oils from Ripe and Unripe Fruits of Piper amalago L. var. medium (Jacq.) Yunck and Piper hispidum Sw.", Journal of Essential Oil Research, 28: 54-58.
5) Nair, M. G. and Burke, B. A., Journal of Agriculture and Food Chemistry, 1990,38, 1093.
6) Terhune, S. J., Hogg, J. W., Bromstein, A. C. and Lawrence, B. M., Canadian Journal of Chemistry, 1975,
53, 3285.
7) Burke, B. and Nair, M., Phytochemistry, 1986,25, 1427.
8) Nair, M. G., Mansingh, A. P. and Burke, B. A., Agricultural and Biological Chemistry, 1986,50, 3053.
9) Machado, S. M. F., Militao, J. S. L. T., Facundo, V. A., Ribeiro, A., Morais, S. M. and Machado, M.
I. L., Journal of Essential Oil Research, 1994,6, 643 (Chemical Abstracts, 122, 101640).
10) Vieira, P. C., DeAlvarenga, M. A., Gottlieb, 0. R. and Gottlieb, H. E., Planta Medica, 1980, 39, 153.
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Understory shrub that can reach heights of 3m.
Has parallel venation, reddish stems and is hispid to the touch.
This information is based an ongoing project dedicated to the inventory and dissemination of information on lepidopteran larvae, their host plants, and their parasitoids in an Ecuadorian montane cloud forest.
N= 636 herbivore associations as of 2012.
Geometridae: Eois beebei (Warren); N=2, Eois cancellata (Warren); N=3, Eois cervina (Warren); N=2, Eois fucosa (Dognin); N=1, Eois nr. fucosa (Dognin); N=11, Eois jifia (Dognin); N=2, Eois nr. fuscicosta (Dognin); N=1, Eois nr. nigricosta (Prout); N=6, Eois nr. pallidicosta (Warren); N=1, Eois zorra (Dognin); N=2, Eois nov. spp.; N=437.
Crambidae: Goniorhynchus hampsoni (Lederer); N=1.
Larval lepidopteran herbivores reared in Napo Province, Ecuador (Yanayacu Biological Station and Center for Creative Studies).
For Piper phylogeny see attached pdf (Jaramillo et al., 2008).
Several subspecies of Piper hispidum have been described:
Piper hispidum hispidum
Piper hispidum laevius
Piper hispidum magnifolium
Piper hispidum substrigosum
Piper hispidum obliquum
Piper hispidum trachydermum
For evolutionary relationship between Piper host plants and the specialist caterpillar genus Eois, see attached pdf (Wilson et al., 2012).
For original publication details of Piper hispidum see: Prodr. Veg. Ind. Occ. 15 1788.
Piper hispidum is native to the lowlands of Mexico and has a pantropical distribution. It is found in the Antilles and from Mexico to southern Brazil.
This information was accessed through Discover Life.
400m-2075m (Based on CAPEA rearings)
Larval lepidopteran herbivores have been reared off Piper hispidum collected from several locations in Napo Province, Ecuador (Yanayacu Biological Station and Center for Creative Studies, Arenillas, Isla de Las Palmas, Chaco, Cordillera de Guacomayos, Aliñahui).
P. hispidum is found commonly in both disturbed and undistrubed sites.
Grows in areas with abundant light.
Has been reported to be used for the treatment of aches and pains in Nicaragua (Coe & Anderson, 1996).
Has been reported to be used for mensturational regulation in Peru (Duke & Vasquez, 1994).
Has been reported to be used for treatment of unrinary tract infections in the Amazon region (Duke & Vasqyez, 1994).
Has been reported to be used to heal wounds and to treat symptoms of cutaneous leishmaniasis, by the Chayahuitas, an Amazonian Peruvian ethnic group (Estrevez et al., 2007).
Has been reported that the leaves of Piper hispidum are used to prepare a tea for the treatment
of female reproductive disorders including amenorrhea, dysmenorrhea, menopause and pain (Michel et al., 2007).
Coe, F.G., Anderson, G.J., 1996. Screening of medicinal plants used by the Garífuna of eastern Nicaragua for bioactive compounds. Journal of Ethnopharmacology 53, 29–50.
Duke, J.A., Vásquez, R., 1994. Amazonian Ethnobotanical Dictionary. CRC Press, Boca Raton, FL, 215 pp.
Estevez, Y., Castillo, D., Pisango, M.T., Arevalo, J., Rojas, R., Alban, J., Deharo, E., Bourdy, G., Sauvain, M., 2007. Evaluation of the leishmanicidal activity of plants used by Peruvian Chayahuita ethnic group. Journal of Ethnopharmacology 114, 254–259.
Michel, J., Duarte, R.E., Bolton, J.L., Huang, Y., Caceres, A., Veliz, M., Soejarto, D.D., Mahady, G.B., 2007. Medical potential of plants used by the Q’eqchi Maya of Livingston, Guatemala for the treatment of women’s health complaints. Journal of Ethnopharmacology 114, 92–101.
Common Name: "Jamaican Pepper"
A number of synonyms for the accepted name, Piper hispidum Sw. have been acknowledged by The Plant List.